Not known Details About https://www.ceesdekker.net
Not known Details About https://www.ceesdekker.net
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‘Sure, that is definitely about correct. I try to find a Bodily idea of biological programs inside a bottom-up way. I do think you can distinguish 3 strains of research in my group at the moment. The primary problems chromosome structure: How can you have a metre-long DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation tactics that allow for us to study how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.
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Nanofabrication of electrodes with sub-5 nm spacing for transport experiments on one molecules and metal clusters
We establish place-of-care diagnostics examination of neglected tropical illnesses within useful resource-constrained settings, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
During the yrs pursuing these discoveries, my investigation passions shifted to biophysics and nanobiology, and I turned fewer involved with the event of nanotube electronics. The main focus of many scientists in the sector also shifted to graphene (in which, funnily sufficient, the very first graphene ribbons were being referred to as ‘nanotubes which might be Lower open together their size’) following the invention of the two-dimensional material in 2004.
Since 2000 he moved to one-molecule biophysics and nanobiology, with exploration from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning cell division https://www.ceesdekker.net with microbes on chip, even though his final interest is in the way of acknowledging artificial cells.
Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA in a very cooperative style
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Dekker began his research on one carbon nanotubes in 1993 when he put in place a brand new line of research to check electrical transport through solitary natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was accomplished inside of a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography procedures have been used to display that these nanotubes are quantum wires at the single-molecule stage, with exceptional Actual physical Homes.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)